Recombinant Human FBXO31, His-tagged

• Cat.No.: FBXO31-28814TH
• Product Overview: Recombinant fragment, corresponding to amino acids 298-539 of Human FBXO31 with an N terminal His tag. Predicted MWt: 28 kDa.

Specification

• Description: Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow.
• Form: Lyophilised:Reconstitute with 138 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: DLIKPGLFKGTYGSHGLEIVMLSFHGRRARGTKITGDPNI PAGQQTVEIDLRHRIQLPDLENQRNFNELSRIVLEVRE RVRQEQQEGGHEAGEGRGRQGPRESQPSPAQPRAEAPS KGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQPFVLPVG VSSRNEDYPRTCRMCFYGTGLIAGHGFTSPERTPGVFILF DEDRFGFVWLELKSFSLYSRVQATFRNADAPSPQAFDE MLKNIQSLTS
• Sequence Similarities: Belongs to the FBXO31 family.Contains 1 F-box domain.

Gene Information

• Gene Name: FBXO31 F-box protein 31 [ Homo sapiens ]
• Official Symbol: FBXO31
• Synonyms: FBXO31; F-box protein 31; F box only protein 31; F-box only protein 31; FBX14; Fbx31; FBXO14; MGC15419
• Gene ID: 79791
• mRNA Refseq: NM_024735
• Protein Refseq: NP_079011
• MIM: 609102
• Uniprot ID: Q5XUX0
• Chromosome Location: 16q24
• Function: cyclin binding