Recombinant Human FDFT1
Cat.No. : | FDFT1-27574TH |
Product Overview : | Recombinant full length Human FDFT1 with an N-terminal proprietary tag; 71.98 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. |
Protein length : | 417 amino acids |
Molecular Weight : | 71.980kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MEFVKCLGHPEEFYNLVRFRVGGKRKVMPKMDQDSLSSSL KTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALD TLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDK HVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGED TERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRL RNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ AVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQY LTTLSQVTEDYVQTGEH |
Sequence Similarities : | Belongs to the phytoene/squalene synthase family. |
Gene Name : | FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens ] |
Official Symbol : | FDFT1 |
Synonyms : | FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; |
Gene ID : | 2222 |
mRNA Refseq : | NM_004462 |
Protein Refseq : | NP_004453 |
MIM : | 184420 |
Uniprot ID : | P37268 |
Chromosome Location : | 8p23.1-p22 |
Pathway : | Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, FPP => cholesterol, organism-specific biosystem; Cholesterol biosynthesis, FPP => |
Function : | farnesyl-diphosphate farnesyltransferase activity; oxidoreductase activity; squalene synthase activity; transferase activity, transferring alkyl or aryl (other than methyl) groups; |
Products Types
◆ Recombinant Protein | ||
FDFT1-3201M | Recombinant Mouse FDFT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FDFT1-1965R | Recombinant Rat FDFT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FDFT1-1505R | Recombinant Rhesus Macaque FDFT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FDFT1-4057H | Recombinant Human FDFT1 Protein, GST-tagged | +Inquiry |
FDFT1-904H | Recombinant Human FDFT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FDFT1-6271HCL | Recombinant Human FDFT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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