"FGF19" Related Products

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Recombinant Human FGF19, His-tagged

Cat.No.: FGF19-27599TH
Product Overview: Recombinant Full length human FGF 19 (minus the signal sequence); a single, non-glycosylated, polypeptide chain of 206 amino acids, M.Wt 23 kDa and containing an N terminal his tag.
Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
Conjugation: HIS
Source: E. coli
Tissue specificity: Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Form: Lyophilised:It is recommended to reconstitute the lyophilized Fibroblast Growth Factor 19 in sterile water to not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 100mM Sodium chloride, 10mM Tris, pH 7.6
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MRGSHHHHHH GMASLAFSDA GPHVHYGWGD PIRLRHLYTS GPHGLSSCFL RIRADGVVDC ARGQSAHSLLEIKAVALRTV AIKGVHSVRY LCMGADGKMQ GLLQYSEEDC AFEEEIRPDG YNVYRSEKHR LPVSLSSAKQ RQLYKNRGFL PLSHFLPMLP MVPEEPEDLR GHLESDMFSS PLETDSMDPF GLVTGLEAVR SPSFEK.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
Gene Name: FGF19 fibroblast growth factor 19 [ Homo sapiens ]
Official Symbol: FGF19
Synonyms: FGF19; fibroblast growth factor 19;
Gene ID: 9965
mRNA Refseq: NM_005117
Protein Refseq: NP_005108
MIM: 603891
Uniprot ID: O95750
Chromosome Location: 11q13.1
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR4 ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem;
Function: fibroblast growth factor receptor binding; growth factor activity; protein binding; protein tyrosine kinase activity;

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