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Recombinant Human GALK1, His-tagged

Cat.No.: GALK1-28118TH
Product Overview: Recombinant full length Human GALK1 with a N terminal His tag. 412 amino acids with a predicted MWt 44.4 kDa including tag.
Description: Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.
Protein length: 392 amino acids
Conjugation: HIS
Molecular Weight: 44.400kDa inclusive of tags
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol
Storage: Please see Notes section
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL
Sequence Similarities: Belongs to the GHMP kinase family. GalK subfamily.
Gene Name: GALK1 galactokinase 1 [ Homo sapiens ]
Official Symbol: GALK1
Synonyms: GALK1; galactokinase 1; GALK; galactokinase;
Gene ID: 2584
mRNA Refseq: NM_000154
Protein Refseq: NP_000145
MIM: 604313
Uniprot ID: P51570
Chromosome Location: 17q23-q25
Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Galactose catabolism, organism-specific biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem;
Function: ATP binding; galactokinase activity; galactose binding; kinase activity; nucleotide binding;

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