Recombinant Human GFAP

• Cat.No.: GFAP-29017TH
• Product Overview: Recombinant full length Human GFAP (amino acids 1-432) with a N terminal proprietary tag; predicted MWt 73.59kDa inclusive of tag.

Specification

• Description: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Protein length: 432 amino acids
• Molecular Weight: 73.590kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Expressed in cells lacking fibronectin.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLA RMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRF ASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETN LRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFL RKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKH EANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVRE AASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVS EGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
• Sequence Similarities: Belongs to the intermediate filament family.

Gene Information

• Gene Name: GFAP glial fibrillary acidic protein [ Homo sapiens ]
• Official Symbol: GFAP
• Synonyms: GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein
• Gene ID: 2670
• mRNA Refseq: NM_001131019
• Protein Refseq: NP_001124491
• MIM: 137780
• Uniprot ID: P14136
• Chromosome Location: 17q21
• Function: integrin binding; structural constituent of cytoskeleton