"GMNN" Related Products

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Recombinant Human GMNN protein, His-tagged

Cat.No.: GMNN-28741TH
Product Overview: Recombinant Human GMNN(1-209aa) fused with His tag was expressed in E. coli.
Description: Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
Source: E. coli
Species: Human
Tag : His
Form: Liquid. In 20mM Tris (pH 8.0), 100mM NaCl, 10% Glycerol
Molecular Mass: 27.6kDa (245aa), confirmed by MALDI-TOF.
AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNPS MKQKQEEIKE NIKNSSVPRR TLKMIQPSAS GSLVGRENEL SAGLSKRKHRNDHLTSTTSS PGVIVPESSE NKNLGGVTQE SFDLMIKENP SSQYWKEVAE KRRKALYEAL KENEKLHKEI EQKDNEIARL KKENKELAEVAEHVQYMAEL IERLNGEPLD NFESLDNQEF DSEEETVEDS LVEDSEIGTC AEGTVSSSTD AKPCI
Purity: > 95% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: GMNN geminin, DNA replication inhibitor [ Homo sapiens ]
Official Symbol: GMNN
Synonyms: GMNN; geminin, DNA replication inhibitor; geminin; Gem;
Gene ID: 51053
mRNA Refseq: NM_015895
Protein Refseq: NP_056979
MIM: 602842
UniProt ID: O75496

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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