Recombinant Human GNAZ

• Cat.No.: GNAZ-31726TH
• Product Overview: Recombinant full length Human G Protein alpha x+z with a N terminal proprietary tag; Predicted MWt 67.16 kDa.

Specification

• Description: The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.
• Protein length: 355 amino acids
• Molecular Weight: 67.160kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLG TSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDS LTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEI TPELLGVMRRLWADQGAQACFSRSSEYHLEDNAAYYLNDL ERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMV DVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQ TSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIR RIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEI YSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
• Sequence Similarities: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Gene Information

• Gene Name: GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide [ Homo sapiens ]
• Official Symbol: GNAZ
• Synonyms: GNAZ; guanine nucleotide binding protein (G protein), alpha z polypeptide; guanine nucleotide-binding protein G(z) subunit alpha
• Gene ID: 2781
• mRNA Refseq: NM_002073
• Protein Refseq: NP_002064
• MIM: 139160
• Uniprot ID: P19086
• Chromosome Location: 22q11.1-q11.2
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; G alpha (z) signalling events, organism-specific biosystem
• Function: G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; guanyl nucleotide binding; guanyl-nucleotide exchange factor activity