"GNMT" Related Products

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Recombinant Human GNMT, His-tagged

Cat.No.: GNMT-28152TH
Product Overview: Recombinant full length protein of Human GNMT with a 20 amino acid His-Tag tag at the N-terminus, 34.9kDa inclusive of tag.
Description: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Protein length: 295 amino acids
Conjugation: HIS
Molecular Weight: 34.900kDa inclusive of tags
Source: E. coli
Tissue specificity: Abundant in liver.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol
Storage: Store at 4°C or at -20°C for long term storage.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD
Sequence Similarities: Belongs to the glycine N-methyltransferase family.
Gene Name: GNMT glycine N-methyltransferase [ Homo sapiens ]
Official Symbol: GNMT
Synonyms: GNMT; glycine N-methyltransferase;
Gene ID: 27232
mRNA Refseq: NM_018960
Protein Refseq: NP_061833
MIM: 606628
Uniprot ID: Q14749
Chromosome Location: 6p12
Pathway: Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem;
Function: folic acid binding; glycine N-methyltransferase activity; glycine binding; protein binding; transferase activity;

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