||Recombinant full length protein, corresponding to amino acids 1-474 of Human Glutathione Synthetase with N terminal His tag, MWt 56kDa.
||Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
||Lyophilised:Reconstitute with 41 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPT SSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDA VSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIA QTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGG LASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAK AWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNI HVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGY MPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQ QELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEE GDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQL KDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCIS ELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVA AGVAVLDNPYPV
||Belongs to the eukaryotic GSH synthase family.