Recombinant Human GSTM2, His-tagged GSTM2-27773TH

Recombinant Human GSTM2, His-tagged


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Recombinant Human GSTM2, His-tagged

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Cat.No. : GSTM2-27773TH
Product Overview : Recombinant full length Human GSTM2 with an N terminal His tag; 238aa, 27.9kDa.
Description : Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Protein length : 218 amino acids
Conjugation : HIS
Molecular Weight : 27.900kDa
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Gene Name : GSTM2 glutathione S-transferase mu 2 (muscle) [ Homo sapiens ]
Official Symbol : GSTM2
Synonyms : GSTM2; glutathione S-transferase mu 2 (muscle); glutathione S transferase M2 (muscle); glutathione S-transferase Mu 2; GST4;
Gene ID : 2946
mRNA Refseq : NM_000848
Protein Refseq : NP_000839
MIM : 138380
Uniprot ID : P28161
Chromosome Location : 1p13.3
Pathway : Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem;
Function : glutathione transferase activity; transferase activity;

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