Recombinant Human GTF2E2, His-tagged

• Cat.No.: GTF2E2-30319TH
• Product Overview: Recombinant full length human TFIIE beta with His tag, purified from an E. coli strain that contains the coding sequence of the protein under the control of T7 promoter.

Specification

• Description: General transcription factor IIE subunit 2 (GTF2E2), also known as transcription initiation factor IIE subunit beta (TFIIE-beta), is a protein that in humans is encoded by the GTF2E2 gene.
• Conjugation: HIS
• Source: E. coli
• Biological activity: 1 unit equals 1 nanogram of purified protein.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the TFIIE beta subunit family.Contains 1 TFIIE beta DNA-binding domain.

Gene Information

• Gene Name: GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa [ Homo sapiens ]
• Official Symbol: GTF2E2
• Synonyms: GTF2E2; general transcription factor IIE, polypeptide 2, beta 34kDa; general transcription factor IIE, polypeptide 2 (beta subunit, 34kD); transcription initiation factor IIE subunit beta; FE; TF2E2; TFIIE B
• Gene ID: 2961
• mRNA Refseq: NM_002095
• Protein Refseq: NP_002086
• MIM: 189964
• Uniprot ID: P29084
• Chromosome Location: 8p12
• Pathway: Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem
• Function: DNA binding; protein binding