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Recombinant Human GUCA2A

Cat.No.: GUCA2A-28752TH
Product Overview: Recombinant full length Guanylin protein (Human) calculated MW 11kDa, with two N terminal extra AA, 96AA.
Description: Heat-stable enterotoxins (STa) are small, cysteine-rich peptides secreted by Escherichia coli that are able to induce diarrhea through the stimulation of an intestine-specific receptor-guanylyl cyclase known as STaR.
Source: E. coli
Tissue specificity: Highly expressed in ileum and colon. Found in plasma.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Water
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: GPVTVQDGNF SFSLESVKKL KDLQEPQEPR VGKLRNFAPI PGEPVVPILC SNPNFPEELK PLCKEPNAQE ILQRLEEIAE DPGTCEICAY AACTGC
Sequence Similarities: Belongs to the guanylin family.
Gene Name: GUCA2A guanylate cyclase activator 2A (guanylin) [ Homo sapiens ]
Official Symbol: GUCA2A
Synonyms: GUCA2A; guanylate cyclase activator 2A (guanylin); GUCA2; guanylin; STARA;
Gene ID: 2980
mRNA Refseq: NM_033553
Protein Refseq: NP_291031
MIM: 139392
Uniprot ID: Q02747
Chromosome Location: 1p35-p34
Pathway: Myometrial Relaxation and Contraction Pathways, organism-specific biosystem;
Function: guanylate cyclase activator activity; hormone activity;

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