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Recombinant Human HLF, His-tagged

Cat.No. : HLF-27715TH
Product Overview : Recombinant full length Human HLF (amino acids 1-295 ) with a N terminal His tag. 315 amino acids with a predicted MWt 35.3 kDa including tag.
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  • Gene Information
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Description : This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Protein length : 295 amino acids
Conjugation : HIS
Molecular Weight : 35.300kDa inclusive of tags
Source : E. coli
Tissue specificity : Highly expressed in liver; lower levels in lung and kidney.
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 1.17% Sodium chloride, 0.002% PMSF
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMEKMSRPLPLNPTFIPPPYG VLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPT VPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIP PSPSQHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHP GIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYE PDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKA RKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIA IRASFLEKENSALRQEVADLRKELGKCKNILAKYEARH GPL
Sequence Similarities : Belongs to the bZIP family. PAR subfamily.Contains 1 bZIP domain.
Gene Name : HLF hepatic leukemia factor [ Homo sapiens ]
Official Symbol : HLF
Synonyms : HLF; hepatic leukemia factor; MGC33822;
Gene ID : 3131
mRNA Refseq : NM_002126
Protein Refseq : NP_002117
MIM : 142385
Uniprot ID : Q16534
Chromosome Location : 17q22
Function : DNA binding; double-stranded DNA binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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