Recombinant Human HPRT1, His-tagged
Cat.No. : | HPRT1-28755TH |
Product Overview : | Recombinant full length Human HPRT with an N-terminal His tag; 238 amino acids with a predicted MWt 26.7 kDa including tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. |
Protein length : | 218 amino acids |
Conjugation : | HIS |
Molecular Weight : | 26.700kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MATRSPGVVI SDDEPGYDLD LFCIPNHYAE DLERVFIPHG LIMDRTERLA RDVMKEMGGH HIVALCVLKG GYKFFADLLD YIKALNRNSD RSIPMTVDFI RLKSYCNDQS TGDIKVIGGD DLSTLTGKNV LIVEDIIDTG KTMQTLLSLV RQYNPKMVKV ASLLVKRTPR SVGYKPDFVG FEIPDKFVVG YALDYNEYFR DLNHVCVISE TGKAKYKA |
Sequence Similarities : | Belongs to the purine/pyrimidine phosphoribosyltransferase family. |
Gene Name : | HPRT1 hypoxanthine phosphoribosyltransferase 1 [ Homo sapiens ] |
Official Symbol : | HPRT1 |
Synonyms : | HPRT1; hypoxanthine phosphoribosyltransferase 1; HPRT; hypoxanthine-guanine phosphoribosyltransferase; HGPRT; Lesch Nyhan syndrome; |
Gene ID : | 3251 |
mRNA Refseq : | NM_000194 |
Protein Refseq : | NP_000185 |
MIM : | 308000 |
Uniprot ID : | P00492 |
Chromosome Location : | Xq26.2 |
Pathway : | Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; |
Function : | guanine phosphoribosyltransferase activity; hypoxanthine phosphoribosyltransferase activity; hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
HPRT1-2696M | Recombinant Mouse HPRT1 Protein, GST-tagged | +Inquiry |
HPRT1-0321H | Recombinant Human HPRT1 Protein (M1-A218), Tag Free | +Inquiry |
HPRT1-2560R | Recombinant Rat HPRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HPRT1-0322H | Recombinant Human HPRT1 Protein (M1-A218), His/Strep tagged | +Inquiry |
HPRT1-1096H | Recombinant Human HPRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HPRT1-5398HCL | Recombinant Human HPRT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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