Recombinant Human IFNG, His-tagged

• Cat.No.: IFNG-28244TH
• Product Overview: Recombinant 143 amino acid fragment, amino acids 24-166, corresponding to the Human mature soluble IFN gamma chain protein, with an amino-terminal hexahistidine tag.

Specification

• Description: This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Released primarily from activated T lymphocytes.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the type II (or gamma) interferon family.

Gene Information

• Gene Name: IFNG interferon, gamma [ Homo sapiens ]
• Official Symbol: IFNG
• Synonyms: IFNG; interferon, gamma; interferon gamma
• Gene ID: 3458
• mRNA Refseq: NM_000619
• Protein Refseq: NP_000610
• MIM: 147570
• Uniprot ID: P01579
• Chromosome Location: 12q14
• Pathway: ATF-2 transcription factor network, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem
• Function: cytokine activity; interferon-gamma receptor binding