"IL28A" Related Products

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Recombinant Human IL28A

Cat.No.: IL28A-29785TH
Product Overview: Recombinant Human IL28A, a 19.6 kDa protein containing 174 amino acid residues.
Description: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Source: E. coli
Biological activity: Biological activity of IL28A-29785TH is determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells.
Form: Lyophilised
Storage: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
Sequences of amino acids: PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV
Sequence Similarities: Belongs to the IL-28/IL-29 family.
Gene Name: IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
Official Symbol: IL28A
Synonyms: IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A;
Gene ID: 282616
mRNA Refseq: NM_172138
Protein Refseq: NP_742150
MIM: 607401
Uniprot ID: Q8IZJ0
Chromosome Location: 19q13.13
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function: cytokine activity;

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