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Recombinant Human ISG15

Cat.No.: ISG15-28728TH
Product Overview: Recombinant full length human ISG15 with Calmodulin tag; 308 amino acids, 34kDa.
Description: ISG15 is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha (IFNA; MIM 147660) and -beta (IFNB; MIM 147640) (Zhao et al.
Source: E. coli
Tissue specificity: Detected in lymphoid cells, striated and smooth muscle, several epithelia and neurons.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 0.1M Sodium chloride, 20mM Tris, 1mM DTT, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SMGWDLTVKM LAGNEFQVSL SSSMSVSELK AQITQKIGVH AFQQRLAVHP SGVALQDRVP LASQGLGPGS TVLLVVDKCD EPLNILVRNN KGRSSTYEVR LTQTVAHLKQ QVSGLEGVQD DLFWLTFEGK PLEDQLPLGE YGLKPLSTVF MNLRLRGGunderlined sequence corresponds to the Calmodulin tag
Sequence Similarities: Contains 2 ubiquitin-like domains.
Gene Name: ISG15 ISG15 ubiquitin-like modifier [ Homo sapiens ]
Official Symbol: ISG15
Synonyms: ISG15; ISG15 ubiquitin-like modifier; G1P2, interferon, alpha inducible protein (clone IFI 15K); ubiquitin-like protein ISG15; IFI15; UCRP;
Gene ID: 9636
mRNA Refseq: NM_005101
Protein Refseq: NP_005092
MIM: 147571
Uniprot ID: P05161
Chromosome Location: 1p36.33
Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem;
Function: protein tag;

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