Recombinant Human LRPAP1

• Cat.No.: LRPAP1-29430TH
• Product Overview: Recombinant full length Human LRPAP1; MWt 39 kDa. Prepared as a fusion protein with a proprietary tag which is cleaved with thrombin. Purified to lower levels of endotoxin.

Specification

• Description: Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene.
• Source: E. coli
• Biological activity: Binds with high affinity to certain members of the low-density lipoprotein (LDL) receptor family such as LRP, gp330/megalin, and the very low-density lipoprotein (VLDL) receptor.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 0.15M Sodium chloride, 0.0067M PBS, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the alpha-2-MRAP family.

Gene Information

• Gene Name: LRPAP1 low density lipoprotein receptor-related protein associated protein 1 [ Homo sapiens ]
• Official Symbol: LRPAP1
• Synonyms: LRPAP1; low density lipoprotein receptor-related protein associated protein 1; A2MRAP, low density lipoprotein related protein associated protein 1 (alpha 2 macroglobulin receptor associated protein 1); alpha-2-macroglobulin receptor-associated protein
• Gene ID: 4043
• mRNA Refseq: NM_002337
• Protein Refseq: NP_002328
• MIM: 104225
• Uniprot ID: P30533
• Chromosome Location: 4p16.3
• Pathway: Lissencephaly gene (LIS1) in neuronal migration and development, organism-specific biosystem; Reelin signaling pathway, organism-specific biosystem; Signaling events mediated by the Hedgehog family, organism-specific biosystem
• Function: asialoglycoprotein receptor activity; heparin binding; lipase binding; low-density lipoprotein particle receptor binding; receptor antagonist activity