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Recombinant Human LTBP1

Cat.No. : LTBP1-29149TH
Product Overview : Recombinant fragment of Human LTBP1 with an N terminal proprietary tag; Predicted MW 36.41kDa.
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  • Gene Information
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Description : The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein length : 98 amino acids
Molecular Weight : 36.410kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Isoform Long is found in fibroblasts.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : CPGGMGYTVSGVHRRRPIHHHVGKG PVFVKPKNTQPVAKSTHPPPLPAKE EPVEALTFSREHGPGVAEPEVATAP PEKEIPSLDQEKTKLEPGQPQLS
Sequence Similarities : Belongs to the LTBP family.Contains 18 EGF-like domains.Contains 4 TB (TGF-beta binding) domains.
Gene Name : LTBP1 latent transforming growth factor beta binding protein 1 [ Homo sapiens ]
Official Symbol : LTBP1
Synonyms : LTBP1; latent transforming growth factor beta binding protein 1; latent-transforming growth factor beta-binding protein 1; TGF beta1 BP 1;
Gene ID : 4052
mRNA Refseq : NM_000627
Protein Refseq : NP_000618
MIM : 150390
Uniprot ID : Q14766
Chromosome Location : 2p22-p21
Pathway : TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : binding; calcium ion binding; growth factor binding; transforming growth factor beta-activated receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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