| Description : |
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. |
| Protein length : |
297 amino acids |
| Molecular Weight : |
58.740kDa inclusive of tags |
| Source : |
Wheat germ |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPK LGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAE HFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDP AFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGI EPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL SKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWY MRARPEDVISEGRGKTH |
| Sequence Similarities : |
Contains 2 rhodanese domains. |
| Gene ID : |
MPST mercaptopyruvate sulfurtransferase [ Homo sapiens ] |
| Official Symbol : |
MPST |
| Synonyms : |
MPST; mercaptopyruvate sulfurtransferase; 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; TST2; |
