Recombinant Human MPZ

• Cat.No.: MPZ-29152TH
• Product Overview: Recombinant full length Human Myelin Protein Zero protein with an N terminal proprietary tag; predicted mwt: 54.12 kDa inclusive of tag.

Specification

• Description: This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies.
• Protein length: 258 amino acids
• Molecular Weight: 54.120kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Found only in peripheral nervous system Schwann cells.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MLRAPAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAI VVYTDREAHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQP EGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKV PTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAAL QRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTK AVSEKKAKGLGESRKDKK
• Sequence Similarities: Belongs to the myelin P0 protein family.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene Information

• Gene Name: MPZ myelin protein zero [ Homo sapiens ]
• Official Symbol: MPZ
• Synonyms: MPZ; myelin protein zero; Charcot Marie Tooth neuropathy 1B , CMT1, CMT1B; myelin protein P0; HMSNIB
• Gene ID: 4359
• mRNA Refseq: NM_000530
• Protein Refseq: NP_000521
• MIM: 159440
• Uniprot ID: P25189
• Chromosome Location: 1q22
• Pathway: Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
• Function: structural molecule activity