Recombinant Human MX1

• Cat.No.: MX1-26961TH
• Product Overview: Recombinant full length Human MX1 (amino acids 1-662) with N terminal proprietary tag; Predicted MWt 98.89 kDa including the tag.

Specification

• Description: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene.
• Protein length: 662 amino acids
• Molecular Weight: 98.890kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENN LCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQS SGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKW RGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHE LITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKT LIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGD RTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKC RGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATV PCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKY GVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEED IRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQY RGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMV RLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKL IRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWD FGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLII QFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKR KFLKERLARLTQARRRLAQFPG
• Sequence Similarities: Belongs to the dynamin family.Contains 1 GED domain.

Gene Information

• Gene Name: MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) [ Homo sapiens ]
• Official Symbol: MX1
• Synonyms: MX1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse); myxovirus (influenza) resistance 1, homolog of murine (interferon inducible protein p78); interferon-induced GTP-binding protein Mx1; IFI 78K; MxA
• Gene ID: 4599
• mRNA Refseq: NM_001144925
• Protein Refseq: NP_001138397
• MIM: 147150
• Uniprot ID: P20591
• Chromosome Location: 21q22.3
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Interferon Signaling, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding