Recombinant Human MYL5, His-tagged

• Cat.No.: MYL5-29364TH
• Product Overview: Recombinant full length Human MYL5 with an N-terminal His tag; 197aa, 22.1 kDa.

Specification

• Description: This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia.
• Protein length: 173 amino acids
• Conjugation: HIS
• Molecular Weight: 22.100kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Expressed in fetal skeletal muscle and retina.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT, 0.002% PMSF
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHVKDDEL DAMLKEASGP INFTMFLNLF GEKLSGTDAEETILNAFKML DPDGKGKINK EYIKRLLMSQ ADKMTAEEVD QMFQFASIDV AGNLMASRKT KKKEGGALRA QRASSNVFSN FEQTQIQEFK EAFTLMDQNR DGFIDKEDLK DTYASLGKTNDYKALSYVIT HGEEKEE
• Sequence Similarities: Contains 3 EF-hand domains.

Gene Information

• Gene Name: MYL5 myosin, light chain 5, regulatory [ Homo sapiens ]
• Official Symbol: MYL5
• Synonyms: MYL5; myosin, light chain 5, regulatory; myosin, light polypeptide 5, regulatory; myosin light chain 5
• Gene ID: 4636
• mRNA Refseq: NM_002477
• Protein Refseq: NP_002468
• MIM: 160782
• Uniprot ID: Q02045
• Chromosome Location: 4p16
• Pathway: Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Regulation of actin cytoskeleton, organism-specific biosystem
• Function: calcium ion binding; structural constituent of muscle