"MYOC" Related Products

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Recombinant Human MYOC

Cat.No.: MYOC-29758TH
Product Overview: Recombinant fragment: QLRKANDQSG RCQYTFSVAS PNESSCPEQS QAMSVIHNLQ RDSSTQRLDL EATKARLSSL ESLLHQLTLD QAARPQETQE GLQRELGTLR RERDQLETQT of Human Myocilin with N terminal proprietary tag, 36.63 kDa.
Description: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Protein length: 100 amino acids
Molecular Weight: 36.630kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: QLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQT
Sequence Similarities: Contains 1 olfactomedin-like domain.
Gene Name: MYOC myocilin, trabecular meshwork inducible glucocorticoid response [ Homo sapiens ]
Official Symbol: MYOC
Synonyms: MYOC; myocilin, trabecular meshwork inducible glucocorticoid response; GLC1A; myocilin; JOAG1; TIGR;
Gene ID: 4653
mRNA Refseq: NM_000261
Protein Refseq: NP_000252
MIM: 601652
Uniprot ID: Q99972
Chromosome Location: 1q23-q24
Function: structural molecule activity;

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