Recombinant Human NAP1L4, His-tagged

• Cat.No.: NAP1L4-29718TH
• Product Overview: Recombinant fragment, corresponding to amino acids 24-375 of Human NAP1L4 with an N terminal His tag. Predicted mwt: 42 kDa

Specification

• Description: This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 95 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Store at 4°C. Upon reconstitution store at -80oC.
• Sequences of amino acids: TEKLTDQVMQNPRVLAALQERLDNV PHTPSSYIETLPKAV KRRINALKQLQVRCAHIEAKFYEEV HDLERKYAALYQP LFDKRREFITGDVEPTDAESEWHSE NEEEEKLAGDMKSKV VVTEKAAATAEEPDPKGIPEFWFTI FRNVDMLSELVQE YDEPILKHLQDIKVKFSDPGQPMSF VLEFHFEPNDYFT NSVLTKTYKMKSEPDKADPFSFEGP EIVDCDGCTIDWKKG KNVTVKTIKKKQKHKGRGTVRTITK QVPNESFFNFFNP LKASGDGESLDEDSEFTLASDFEIG HFFRERIVPRAVLYFTGEAIEDDDN FEEGEEGEEEELEGDEEGEDEDDAE INP KV

Gene Information

• Gene Name: NAP1L4 nucleosome assembly protein 1-like 4 [ Homo sapiens ]
• Official Symbol: NAP1L4
• Synonyms: NAP1L4; nucleosome assembly protein 1-like 4; NAP2
• Gene ID: 4676
• mRNA Refseq: NM_005969
• Protein Refseq: NP_005960
• MIM: 601651
• Uniprot ID: Q99733
• Chromosome Location: 11p15.5
• Function: unfolded protein binding