Recombinant Human Neurotrophic Tyrosine Kinase, Receptor, Type 2
Cat.No. : | NTRK2-496H |
- Specification
- Gene Information
- Related Products
Cat. No. : | NTRK2-496H |
Description : | Tropomyosin-related kinase B (TrkB) is a receptor for neurotrophins, a family of closely related proteins that are important physiological regulators of the survival of specific neurons within the peripheral nervous system (PNS) of vertebrates. TrkB is an independent prognostic marker in patients with gastric cancer and appears to be associated with metastatic potential. Trk-B pathway down-regulation may be the major pathogenesis for Major depressive disorder (MDD). |
Molecular Weight : | The predicted molecular weight of Recombinant Human TrkB is Mr 71 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 120-130 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at-20°C to -70℃. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | NTRK2 neurotrophic tyrosine kinase, receptor, type 2 [ Homo sapiens ] |
Synonyms : | NTRK2; neurotrophic tyrosine kinase, receptor, type 2; TRKB; GP145-TrkB; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; tyrosine kinase receptor B; BDNF/NT-3 growth factors receptor; EC 2.7.10.1 |
Gene ID : | 4915 |
mRNA Refseq : | NM_001007097 |
Protein Refseq : | NP_001007098 |
MIM : | 600456 |
UniProt ID : | Q16620 |
Chromosome Location : | 9q22.1 |
Pathway : | MAPK signaling pathway; Neurotrophin signaling pathway; Signalling by NGF |
Function : | ATP binding; neurotrophin receptor activity; nucleotide binding; protein binding; transferase activity; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
NTRK2-379H | Recombinant Human NTRK2 Protein, His-tagged | +Inquiry |
NTRK2-3764R | Recombinant Rat NTRK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ntrk2-4523M | Recombinant Mouse Ntrk2 Protein, Myc/DDK-tagged | +Inquiry |
NTRK2-2937R | Recombinant Rhesus Macaque NTRK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK2-469H | Recombinant Human NTRK2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NTRK2-1300RCL | Recombinant Rat NTRK2 cell lysate | +Inquiry |
NTRK2-1024CCL | Recombinant Canine NTRK2 cell lysate | +Inquiry |
NTRK2-1843MCL | Recombinant Mouse NTRK2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1629 | TrkB Functional Assay Kit | +Inquiry |
Kit-1547 | U2OS TrkB Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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