Recombinant Human NCR1
Cat.No. : | NCR1-27989TH |
Product Overview : | Recombinant fragment, corresponding to the extracellular Ig-like domain, amino acids 1-22/255 of Human NCR1 |
- Specification
- Gene Information
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Description : | Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. NCR1 has also been designated as CD335 (cluster of differentiation 335). |
Source : | E. coli |
Tissue specificity : | Selectively expressed by both resting and activated NK cells. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS, 1mM EDTA, pH 7.4 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MQQQTLPKPF IWAEPHFMVP KEKQVTICCQ GNYGAVEYQL HFEGSLFAVD RPKPPERINKVKFYIPDMNS RMAGQYSCIY RVGELWSEPS NLLDLVVTEM YDTPTLSVHP GPEVISGEEVTFYCRLDTAT SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV TTAHRGTYRX FGSYNNHAWSFPSEPVKLLV TGDIENTSLA PEDPTFSADT WGTYLLTTET GLQKDHALWD HTAQN |
Sequence Similarities : | Belongs to the natural cytotoxicity receptor (NCR) family.Contains 2 Ig-like (immunoglobulin-like) domains. |
Gene Name : | NCR1 natural cytotoxicity triggering receptor 1 [ Homo sapiens ] |
Official Symbol : | NCR1 |
Synonyms : | NCR1; natural cytotoxicity triggering receptor 1; LY94, lymphocyte antigen 94 (mouse) homolog (activating NK receptor; NK p46); CD335; NK p46; NKP46; |
Gene ID : | 9437 |
mRNA Refseq : | NM_001145457 |
Protein Refseq : | NP_001138929 |
MIM : | 604530 |
Uniprot ID : | O76036 |
Chromosome Location : | 19 |
Pathway : | Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; |
Function : | receptor activity; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
NCR1-3582R | Recombinant Rat NCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NCR1-400H | Recombinant Human NCR1 Protein, Fc-tagged | +Inquiry |
NCR1-472H | Recombinant Human NCR1 Protein, MYC/DDK-tagged | +Inquiry |
Ncr1-8798R | Recombinant Rat Ncr1 protein(Met1-Asn255), hFc-tagged | +Inquiry |
NCR1-204H | Recombinant Human NCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NCR1-1244RCL | Recombinant Rat NCR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIn some cancer immunotherapies, the expression level of NCR1 protein may affect the efficacy of the treatment. High levels of NCR1 expression may predict a better prognosis.
Inhibition of NCR1 expression by gene knockout technology can alleviate the symptoms of autoimmune diseases and provide new ideas and methods for the treatment of autoimmune diseases.
There are currently no drugs that directly target the NCR1 protein, but there are some drugs that can affect the activity of the immune system and thus indirectly affect the expression level of the NCR1 protein.
Yes, there are polymorphisms in the NCR1 gene, some of which may increase an individual's susceptibility to certain diseases such as inflammatory diseases and autoimmune diseases.
There are currently no specific antibodies or drugs against the NCR1 protein, but there are some studies that are exploring the development of therapies against the NCR1 protein.
The function and mechanism of action of NCR1 protein can be studied by gene knockout or knockdown techniques. In addition, techniques such as protein spectroscopy can be used to identify proteins that interact with NCR1 proteins and their sites of action.
Customer Reviews (3)
Write a reviewIn drug screening experiments, it was found that it had good selectivity for specific disease-related targets.
It has been observed in cell culture experiment that it can promote the growth and proliferation of cells.
It has a wide range of applications and can be used in various biological experiments.
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