Recombinant Human NCS1, His-tagged

• Cat.No.: NCS1-29298TH
• Product Overview: Recombinant full length Human NCS1 with a C terminal His tag. Amino acids 1-190 , predicted mwt: 23 kDa

Specification

• Description: This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQFFPFGD PTKFATFVFN VFDENKDGRI EFSEFIQALS VTSRGTLDEK LRWAFKLYDL DNDGYITRNE MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DGKLTLQEFQ EGSKADPSIV QALSLYDGLV LEHHHHHH
• Sequence Similarities: Belongs to the recoverin family.Contains 4 EF-hand domains.

Gene Information

• Gene Name: NCS1 neuronal calcium sensor 1 [ Homo sapiens ]
• Official Symbol: NCS1
• Synonyms: NCS1; neuronal calcium sensor 1; FREQ, frequenin (Drosophila) homolog , frequenin homolog (Drosophila); NCS 1
• Gene ID: 23413
• mRNA Refseq: NM_001128826
• Protein Refseq: NP_001122298
• MIM: 603315
• Uniprot ID: P62166
• Chromosome Location: 9q34.11
• Function: calcium ion binding; protein binding