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Recombinant Human NDE1, His-tagged

Cat.No. : NDE1-28795TH
Product Overview : Recombinant full length Human NDE1, isoform 2 (amino acids 1-335) with N terminal His tag; 355 amino acids, 39.9 kDa.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants.
Protein length : 335 amino acids
Conjugation : HIS
Molecular Weight : 39.900kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.08% DTT, 1.17% Sodium chloride
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMEDSGKTFSSEEEEANYWKD LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDL AQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHR GPSSSLNTPGSFRRGLDDSTGGTPLTPAARISALNIVGDL LRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
Sequence Similarities : Belongs to the nudE family.
Gene Name : NDE1 nudE nuclear distribution gene E homolog 1 (A. nidulans) [ Homo sapiens ]
Official Symbol : NDE1
Synonyms : NDE1; nudE nuclear distribution gene E homolog 1 (A. nidulans); nuclear distribution protein nudE homolog 1; FLJ20101; NUDE;
Gene ID : 54820
mRNA Refseq : NM_001143979
Protein Refseq : NP_001137451
MIM : 609449
Uniprot ID : Q9NXR1
Chromosome Location : 16p13.11
Pathway : Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; DNA Replication, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem;
Function : microtubule binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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