Recombinant Human NDUFAF2, His-tagged

• Cat.No.: NDUFAF2-30238TH
• Product Overview: Recombinant full length Human Mimitin with an N terminal His tag; 189 amino acids with tag, Predicted MWt 22 kDa.

Specification

• Description: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.
• Protein length: 169 amino acids
• Conjugation: HIS
• Molecular Weight: 22.000kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 200mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGWSQ DLFRALWRSLSREVKEHVGTDQFGN KYYYIPQYKNWRGQTIREKRIVEAA NKKEVDYEAGDIPTEWEAWIRRTRK TPPTMEEILKNEKHREEIKIKSQDF YEKEKLLSKETSEELLPPPVQTQIK GHASAPYFGKEEPSVAPSSTGKTFQ PGSWMPRDGKSHNQ
• Sequence Similarities: Belongs to the complex I NDUFA12 subunit family.

Gene Information

• Gene Name: NDUFAF2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 [ Homo sapiens ]
• Official Symbol: NDUFAF2
• Synonyms: NDUFAF2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2; NDUFA12 like , NDUFA12L; mimitin, mitochondrial; B17.2L; mimitin; MMTN; Myc induced mitochondrial protein
• Gene ID: 91942
• mRNA Refseq: NM_174889
• Protein Refseq: NP_777549
• MIM: 609653
• Uniprot ID: Q8N183
• Chromosome Location: 5q12.1
• Pathway: Validated targets of C-MYC transcriptional activation, organism-specific biosystem
• Function: NADH dehydrogenase (ubiquinone) activity; electron carrier activity