"NDUFS4" Related Products

Recombinant Human NDUFS4

Cat.No.: NDUFS4-28208TH
Product Overview: Recombinant full length mature Human Ndufs4. 134 amino acids with a predicted MWt 15.5 kDa.
Description: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
Protein length: 133 amino acids
Molecular Weight: 15.500kDa
Source: E. coli
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 30% Glycerol
Storage: Please see Notes section
Sequences of amino acids: MAQDQTQDTQ LITVDEKLDI TTLTGVPEEH IKTRKVRIFV PARNNMQSGV NNTKKWKMEF DTRERWENPL MGWASTADPL SNMVLTFSTK EDAVSFAEKN GWSYDIEERK VPKPKSKSYG ANFSWNKRTR VSTK
Sequence Similarities: Belongs to the complex I NDUFS4 subunit family.
Gene Name: NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) [ Homo sapiens ]
Official Symbol: NDUFS4
Synonyms: NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 4 (18kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; AQDQ; CI 18
Gene ID: 4724
mRNA Refseq: NM_002495
Protein Refseq: NP_002486
MIM: 602694
Uniprot ID: O43181
Chromosome Location: 5q11.1
Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem;
Function: NADH dehydrogenase (ubiquinone) activity; contributes_to NADH dehydrogenase (ubiquinone) activity; oxidoreductase activity, acting on NADH or NADPH;

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