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Recombinant Human NFATC3

Cat.No. : NFATC3-27538TH
Product Overview : Recombinant full length Human NFAT4 Isoform 2 with N terminal proprietary tag; MW: 143.55 inclusive of tag
  • Specification
  • Gene Information
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Description : The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Protein length : 1068 amino acids
Molecular Weight : 143.550kDa
Source : Wheat germ
Tissue specificity : Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, hear
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDD CASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQL QSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRES SLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAA ARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAE VCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSG LGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFT WSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPK THHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKV LEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRK NTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDG RPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHF YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVT SSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS SYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQ SMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHS GSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDP ASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDDQFIS DLEHQPSGSAEKWPNHSVLSCPAPFWRI
Sequence Similarities : Contains 1 RHD (Rel-like) domain.
Gene Name : NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 [ Homo sapiens ]
Official Symbol : NFATC3
Synonyms : NFATC3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; nuclear factor of activated T-cells, cytoplasmic 3; NFAT4; NFATX;
Gene ID : 4775
mRNA Refseq : NM_004555
Protein Refseq : NP_004546
MIM : 602698
Uniprot ID : Q12968
Chromosome Location : 16q22
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem;
Function : DNA binding; chromatin binding; sequence-specific DNA binding transcription factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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