Description : |
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. |
Protein length : |
1068 amino acids |
Molecular Weight : |
143.550kDa |
Source : |
Wheat germ |
Tissue specificity : |
Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, hear |
Form : |
Liquid |
Purity : |
Proprietary Purification |
Storage buffer : |
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : |
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDD CASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQL QSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRES SLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAA ARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAE VCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSG LGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFT WSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPK THHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKV LEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRK NTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDG RPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHF YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVT SSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS SYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQ SMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHS GSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDP ASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDDQFIS DLEHQPSGSAEKWPNHSVLSCPAPFWRI |
Sequence Similarities : |
Contains 1 RHD (Rel-like) domain. |