Recombinant Human NKRF, His-tagged

• Cat.No.: NKRF-29050TH
• Product Overview: Recombinant fragment, corresponding to amino acids 299-690 of Human NKRF with a N terminal His tag; predicted MWt 45 kDa:

Specification

• Description: This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:reconstitution with 110 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: QIGMSSYEFPPALKPPEDLVVLGKDASGQPIFNASAKHWT NFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTW RCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQP TYPSVKSSQCHTGSSPRGSGKKKDIKDLVVYENSSNPVCT LNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEA VGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDV ISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGG LGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQ IIRNYARSESHTDLTFSRELTNDERKQIHQIAQKYGLK SKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYEL VMPQAN

Gene Information

• Gene Name: NKRF NFKB repressing factor [ Homo sapiens ]
• Official Symbol: NKRF
• Synonyms: NKRF; NFKB repressing factor; NF kappaB repressing factor; NF-kappa-B-repressing factor; ITBA4; NRF
• Gene ID: 55922
• mRNA Refseq: NM_001173487
• Protein Refseq: NP_001166958
• MIM: 300440
• Uniprot ID: O15226
• Chromosome Location: Xq24
• Function: DNA binding; double-stranded RNA binding