Recombinant Human NT5C2, His-tagged

• Cat.No.: NT5C2-29445TH
• Product Overview: Recombinant full length Human NT5C2 protein with an N terminal His tag; 581 amino acids with the tag; predicted mwt: 67.1 kDa.

Specification

• Description: This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5-monophosphate and other purine nucleotides.
• Protein length: 561 amino acids
• Conjugation: HIS
• Molecular Weight: 67.100kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride, 0.02% DTT, 0.002% PMSF
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSTSWSDRLQ NAADMPANMD KHALKKYRRE AYHRVFVNRS LAMEKIKCFG FDMDYTLAVY KSPEYESLGF ELTVERLVSI GYPQELLSFA YDSTFPTRGL VFDTLYGNLL KVDAYGNLLV CAHGFNFIRG PETREQYPNK FIQRDDTERF YILNTLFNLPETYLLACLVD FFTNCPRYTS CETGFKDGDL FMSYRSMFQD VRDAVDWVHY KGSLKEKTVE NLEKYVVKDG KLPLLLSRMK EVGKVFLATN SDYKYTDKIM TYLFDFPHGP KPGSSHRPWQ SYFDLILVDA RKPLFFGEGT VLRQVDTKTG KLKIGTYTGP LQHGIVYSGG SSDTICDLLGAKGKDILYIG DHIFGDILKS KKRQGWRTFL VIPELAQELH VWTDKSSLFE ELQSLDIFLA ELYKHLDSSS NERPDISSIQ RRIKKVTHDM DMCYGMMGSL FRSGSRQTLF ASQVMRYADL YAASFINLLY YPFSYLFRAA HVLMPHESTV EHTHVDINEM ESPLATRNRT SVDFKDTDYKRHQLTRSISE IKPPNLFPLA PQEITHCHDE DDDEEEEEEE E
• Sequence Similarities: Belongs to the 5(3)-deoxyribonucleotidase family.

Gene Information

• Gene Name: NT5C2 5-nucleotidase, cytosolic II [ Homo sapiens ]
• Official Symbol: NT5C2
• Synonyms: NT5C2; 5-nucleotidase, cytosolic II; 5 nucleotidase (purine), cytosolic type B , NT5B; cytosolic purine 5-nucleotidase; cN II; GMP; PNT5; purine 5 nucleotidase
• Gene ID: 22978
• mRNA Refseq: NM_001134373
• Protein Refseq: NP_001127845
• MIM: 600417
• Uniprot ID: P49902
• Chromosome Location: 10q24.32
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem
• Function: 5-nucleotidase activity; hydrolase activity; metal ion binding; nucleotide binding; protein binding