Recombinant Human PAX3, GST-tagged
Cat.No. : | PAX3-29056TH |
Product Overview : | Recombinant Human PAX3 (1 a.a. - 484 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 79.9 kDa |
AA Sequence : | MTTLAGAVPRMMRPGPGQNYPRSGF PLEVSTPLGQGRVNQLGGVFINGRP LPNHIRHKIVEMAHHGIRPCVISRQ LRVSHGCVSKILCRYQETGSIRPGA IGGSKPKQVTTPDVEKKIEEYKREN PGMFSWEIRDKLLKDAVCDRNTVPS VSSISRILRSKFGKGEEEEADLERK EAEESEKKAKHSIDGILSERASAPQ SDEGSDIDSEPDLPLKRKQRRSRTT FTAEQLEELERAFERTHYPDIYTRE ELAQRAKLTEARVQVWFSNRRARWR KQAGANQLMAFNHLIPGGFPPTAMP TLPTYQLSETSYQPTSIPQAVSDPS STVHRPQPLPPSTVHQSTIPSNPDS SSAYCLPSTRHGFSSYTDSFVPPSG PSNPMNPTIGNGLSPQVMGLLTNHG GVPHQPQTDYALSPLTGGLEPTTTV SASCSQRLDHMKSLDSLPTSQSYCP PTYSTTGYSMDPVTGYQYGQYGQSA FHYLKPDIA |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | PAX3 paired box 3 [ Homo sapiens (human) ] |
Official Symbol : | PAX3 |
Synonyms : | PAX3; WS1; WS3; CDHS; HUP2; paired box 3; paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; paired box homeotic gene 3 |
Gene ID : | 5077 |
mRNA Refseq : | NM_181458 |
Protein Refseq : | NP_852123 |
MIM : | 606597 |
UniProt ID : | P23760 |
Chromosome Location : | 2q35 |
Pathway : | Neural Crest Differentiation; Regulation of retinoblastoma protein; Transcriptional misregulation in cancer |
Function : | HMG box domain binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; chromatin binding |
Products Types
◆ Recombinant Protein | ||
PAX3-58H | Recombinant Human PAX3 Protein, C-His tagged | +Inquiry |
Pax3-4685M | Recombinant Mouse Pax3 Protein, Myc/DDK-tagged | +Inquiry |
PAX3-6517M | Recombinant Mouse PAX3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PAX3-3801H | Recombinant Human PAX3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PAX3-5842C | Recombinant Chicken PAX3 | +Inquiry |
◆ Lysates | ||
PAX3-3418HCL | Recombinant Human PAX3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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