"PDXP" Related Products

Recombinant Human PDXP, His-tagged

Cat.No.: PDXP-30082TH
Product Overview: Recombinant full length Human PDXP with N terminal His tag; 316aa, 33.8kDa.
Description: Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al.
Protein length: 296 amino acids
Conjugation: HIS
Molecular Weight: 33.800kDa inclusive of tags
Source: E. coli
Tissue specificity: Ubiquitous. Highly expressed in all the regions of central nerve system except the spinal cord. Also expressed at high level in liver and testis. In fetus, it is weakly expressed in all organs except brain.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED
Sequence Similarities: Belongs to the HAD-like hydrolase superfamily.
Gene Name: PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase [ Homo sapiens ]
Official Symbol: PDXP
Synonyms: PDXP; pyridoxal (pyridoxine, vitamin B6) phosphatase; pyridoxal phosphate phosphatase; dJ37E16.5; FLJ32703;
Gene ID: 57026
mRNA Refseq: NM_020315
Protein Refseq: NP_064711
MIM: 609246
Uniprot ID: Q96GD0
Chromosome Location: 22q12.3
Pathway: Metabolic pathways, organism-specific biosystem; Vitamin B6 metabolism, organism-specific biosystem; Vitamin B6 metabolism, conserved biosystem;
Function: heat shock protein binding; hydrolase activity; metal ion binding; phosphoprotein phosphatase activity; phosphoserine phosphatase activity;

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