"PEA15" Related Products

Recombinant Human PEA15

Cat.No.: PEA15-30834TH
Product Overview: Recombinant full length Human PEA15; amino acids 1-130 , 15kDa.
Description: This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.
Source: E. coli
Tissue specificity: Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals wi
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 7.5
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA
Sequence Similarities: Contains 1 DED (death effector) domain.
Gene Name: PEA15 phosphoprotein enriched in astrocytes 15 [ Homo sapiens ]
Official Symbol: PEA15
Synonyms: PEA15; phosphoprotein enriched in astrocytes 15; astrocytic phosphoprotein PEA-15; HMAT1; homolog of mouse MAT 1 oncogene; HUMMAT1H; MAT1; MAT1H; PEA 15; PED; Phosphoprotein enriched in astrocytes; 15kD;
Gene ID: 8682
mRNA Refseq: NM_003768
Protein Refseq: NP_003759
MIM: 603434
Uniprot ID: Q15121
Chromosome Location: 1q21.1
Function: protein binding;

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