Recombinant Human PGK1
Cat.No. : | PGK1-30891TH |
Product Overview : | Recombinant full length protein: , corresponding to amino acids 1-417 of Human PGK1 |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19. |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 1mM DTT, pH 8 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MSLSNKLTLD KLDVKGKRVV MRVDFNVPMK NNQITNNQRI KAAVPSIKFC LDNGAKSVVL MSHLGRPDGV PMPDKYSLEP VAVELKSLLG KDVLFLKDCV GPEVEKACAN PAAGSVILLE NLRFHVEEEG KGKDASGNKV KAEPAKIEAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVN LPQKAGGFLM KKELNYFAKA LESPERPFLA ILGGAKVADK IQLINNMLDK VNEMIIGGGM AFTFLKVLNN MEIGTSLFDE EGAKIVKDLM SKAEKNGVKI TLPVDFVTAD KFDENAKTGQ ATVASGIPAG WMGLDCGPES SKKYAEAVTR AKQIVWNGPV GVFEWEAFAR GTKALMDEVV KATSRGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSNI |
Sequence Similarities : | Belongs to the phosphoglycerate kinase family. |
Gene Name : | PGK1 phosphoglycerate kinase 1 [ Homo sapiens ] |
Official Symbol : | PGK1 |
Synonyms : | PGK1; phosphoglycerate kinase 1; |
Gene ID : | 5230 |
mRNA Refseq : | NM_000291 |
Protein Refseq : | NP_000282 |
MIM : | 311800 |
Uniprot ID : | P00558 |
Chromosome Location : | Xq13.3 |
Pathway : | Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem; |
Function : | ATP binding; nucleotide binding; phosphoglycerate kinase activity; phosphoglycerate kinase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Pgk1-4819M | Recombinant Mouse Pgk1 Protein, Myc/DDK-tagged | +Inquiry |
PGK1-529C | Recombinant Cynomolgus Monkey PGK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pgk1-1355M | Recombinant Mouse Pgk1 protein(Met1-Val417), His-tagged | +Inquiry |
PGK1-4067R | Recombinant Rat PGK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGK1-1660H | Recombinant Human PGK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PGK1-547MCL | Recombinant Mouse PGK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPGK1 dysfunction has been associated with neurological conditions like Alzheimer's disease and Parkinson's disease due to its impact on cellular energy metabolism.
PGK1 is often upregulated in cancer cells, aiding their rapid growth and proliferation by enhancing glycolysis, known as the Warburg effect.
Research suggests that targeting PGK1 could potentially be a strategy for cancer therapy by disrupting the energy production in cancer cells.
Several compounds that modulate PGK1 activity are being studied, but none have reached widespread clinical use yet.
Yes, elevated levels of PGK1 have been identified in certain cancers, making it a potential biomarker for cancer detection and prognosis.
Customer Reviews (3)
Write a reviewmanufacturers may offer customization options, allowing researchers to tailor the PGK1 protein to their specific needs.
This may include options like different formulations, protein modifications, or tagging techniques. Customization can enhance the versatility of the protein and optimize its utility in the intended research.
They can also address any questions or concerns regarding the PGK1 protein, thereby facilitating smooth and efficient research execution.
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