Recombinant Human PGK1, His-tagged

• Cat.No.: PGK1-30893TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1-409 of Human PGK1 with N terminal His tag. MWt 47kDa

Specification

• Description: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitution with 86 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: (Amino acid sequence (Sequence determined by 5 Sequencing))MSLSNKLTLDKLDVKGKRVVMRVDFN VPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHL GRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEV EKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKA EPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVA DKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLF DEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENA KTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQI VWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIG GGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLP
• Sequence Similarities: Belongs to the phosphoglycerate kinase family.

Gene Information

• Gene Name: PGK1 phosphoglycerate kinase 1 [ Homo sapiens ]
• Official Symbol: PGK1
• Synonyms: PGK1; phosphoglycerate kinase 1
• Gene ID: 5230
• mRNA Refseq: NM_000291
• Protein Refseq: NP_000282
• MIM: 311800
• Uniprot ID: P00558
• Chromosome Location: Xq13.3
• Pathway: Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem
• Function: ATP binding; nucleotide binding; phosphoglycerate kinase activity; phosphoglycerate kinase activity; transferase activity