Recombinant Human Human PIK3CB, His-tagged
Cat.No. : | PIK3CB-31766TH |
Product Overview : | Recombinant full length Human PIK3CB with N-terminal His tag and recombinant full length Human PIK3R1, untagged, co expressed in a Baculovirus infected Sf9 cell expression system, 124 kDa,and 83kDa respectively. |
- Specification
- Gene Information
- Related Products
Description : | Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al. |
Conjugation : | HIS |
Biological activity : | Specific Activity: 7.9 pmol/min/μg.A 50 μl kinase reaction is conducted in a buffer containing 10 mM Tris-HCl (pH 7.5), 50 mM NaCl, 5 mM MgCl2, 5 μM ATP, 17 μg Phosphoinositol-4,5-Bisphosphate, and 150 ng enzyme for 90 minutes at room temperature. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 30% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Gene Name : | PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide [ Homo sapiens ] |
Official Symbol : | PIK3CB |
Synonyms : | PIK3CB; phosphoinositide-3-kinase, catalytic, beta polypeptide; PIK3C1; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; |
Gene ID : | 5291 |
mRNA Refseq : | NM_006219 |
Protein Refseq : | NP_006210 |
MIM : | 602925 |
Uniprot ID : | P42338 |
Chromosome Location : | 3q21-qter |
Pathway : | 3-phosphoinositide biosynthesis, conserved biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; |
Function : | 1-phosphatidylinositol-3-kinase activity; ATP binding; binding; insulin receptor substrate binding; kinase activity; |
Products Types
◆ Recombinant Protein | ||
PIK3CB-01H | Recombinant Human PIK3CB/PIK3R2 Protein, His-tagged | +Inquiry |
PIK3CB-6738M | Recombinant Mouse PIK3CB Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3CB-4121R | Recombinant Rat PIK3CB Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3CB-3861H | Recombinant Human PIK3CB Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3CB&PIK3R1-155H | Active Recombinant Human PIK3CB/PIK3R1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
PIK3CB-3188HCL | Recombinant Human PIK3CB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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