"PLA2G1B" Related Products

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Recombinant Human PLA2G1B, His-tagged

Cat.No.: PLA2G1B-31023TH
Product Overview: Recombinant full length protein, corresponding to amino acids 23-148 of Human PLA2G1B, with an N-Terminal 16 amino acid His tag.
Description: Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al.
Conjugation: HIS
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: None0.05M Acetate buffer pH 4.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNNYGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFLLDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAICFSKAPYNKA HKNLDTKKYC QS
Sequence Similarities: Belongs to the phospholipase A2 family.
Gene Name: PLA2G1B phospholipase A2, group IB (pancreas) [ Homo sapiens ]
Official Symbol: PLA2G1B
Synonyms: PLA2G1B; phospholipase A2, group IB (pancreas); PLA2, PLA2A, PPLA2; phospholipase A2;
Gene ID: 5319
mRNA Refseq: NM_000928
Protein Refseq: NP_000919
MIM: 172410
Uniprot ID: P04054
Chromosome Location: 12q23-qter
Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem;
Function: bile acid binding; calcium ion binding; calcium ion binding; calcium-dependent phospholipase A2 activity; cell surface binding;

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