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Recombinant Human PLS3

Cat.No. : PLS3-30836TH
Product Overview : Recombinant full length Human T Plastin with a N terminal proprietary tag; Predicted MWt 95.3 kDa including the tag.
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  • Gene Information
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Description : Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.
Protein length : 630 amino acids
Molecular Weight : 95.300kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Expressed in a variety of organs, including muscle, brain, uterus and esophagus.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHEL FKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYI FQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAV GDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLA LNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFH LENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPR IDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREE RTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPV DWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKAN DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLID AIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV YALPEDLVEVKPKMVMTVFACLMGRGMKRV
Sequence Similarities : Contains 2 actin-binding domains.Contains 4 CH (calponin-homology) domains.Contains 2 EF-hand domains.
Gene Name : PLS3 plastin 3 [ Homo sapiens ]
Official Symbol : PLS3
Synonyms : PLS3; plastin 3; plastin 3 (T isoform); plastin-3; T plastin;
Gene ID : 5358
mRNA Refseq : NM_001136025
Protein Refseq : NP_001129497
MIM : 300131
Uniprot ID : P13797
Chromosome Location : Xq23
Function : actin binding; calcium ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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