Recombinant Human POLR2L

• Cat.No.: POLR2L-30688TH
• Product Overview: Recombinant full length human POLR2L with proprietary tag.

Specification

• Description: This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa [ Homo sapiens ]
• Official Symbol: POLR2L
• Synonyms: POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; polymerase (RNA) II (DNA directed) polypeptide L (7.6kD); DNA-directed RNA polymerases I, II, and III subunit RPABC5; hRPB7.6; hsRPB10b; RBP10; RPABC5; RPB7.6; RPB10beta
• Gene ID: 5441
• mRNA Refseq: NM_021128
• Protein Refseq: NP_066951
• MIM: 601189
• Uniprot ID: P62875
• Chromosome Location: 11p15
• Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem
• Function: DNA binding; DNA-directed RNA polymerase activity; metal ion binding; contributes_to protein kinase activity; zinc ion binding