"Cx3cl1" Related Products

Expand
Expand

Recombinant Rat Cx3cl1 Chemokine (C-X3-C Motif) Ligand 1

Cat. No. : Cx3cl1-128R
Description : Fractalkine (FKN) is a transmembrane mucin-chemokine hybrid molecule expressed on activated endothelium that mediates attachment and firm adhesion of T cells, monocytes and NK cells. FKN plays an important proinflammatory role in rheumatoid arthritis (RA) pathogenesis as characterized by induction of synovial angiogenesis, chemotaxis, activation of monocytes and T cells as well as the stimulation of proliferation and synthesis of matrix degrading enzymes (matrix metalloproteinases, MMP) in synovial fibroblasts. Fractalkine thus may represent a novel target molecule for therapeutic intervention in RA. FKN is also an essential biomarker for predicting the prognosis of patients with colorectal cancer (CRC).
Molecular Weight : The predicted molecular weight of Recombinant Rat Fractalkine is Mr 33 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Cx3cl1 chemokine (C-X3-C motif) ligand 1 [ Rattus norvegicus ]
Synonyms : Cx3cl1; chemokine (C-X3-C motif) ligand 1; Cx3c; Scyd1; fractalkine; small inducible cytokine subfamily D, 1; small inducible cytokine subfamily D 1
Gene ID : 89808
mRNA Refseq : NM_134455
Protein Refseq : NP_604450
UniProt ID : O55145
Chromosome Location : 19p12
Pathway : Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : chemokine activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.