Recombinant Human PPP3CA, His-tagged

• Cat.No.: PPP3CA-26743TH
• Product Overview: Recombinant full length Human Calcineurin A Isoform 2 with an N terminal His tag; 534 amino acids with tag, MWt 60.0 kDa.

Specification

• Protein length: 511 amino acids
• Conjugation: HIS
• Molecular Weight: 60.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, 1mM EDTA, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHTGSMS EPKAIDPKLSTTDRVVKAVPFPPSH RLTAKEVFDNDGKPRVDILKAHLMK EGRLEESVALRIITEGASILRQEKN LLDIDAPVTVCGDIHGQFFDLMKLF EVGGSPANTRYLFLGDYVDRGYFSI ECVLYLWALKILYPKTLFLLRGNHE CRHLTEYFTFKQECKIKYSERVYDA CMDAFDCLPLAALMNQQFLCVHGGL SPEINTLDDIRKLDRFKEPPAYGPM CDILWSDPLEDFGNEKTQEHFTHNT VRGCSYFYSYPAVCEFLQHNNLLSI LRAHEAQDAGYRMYRKSQTTGFPSL ITIFSAPNYLDVYNNKAAVLKYENN VMNIRQFNCSPHPYWLPNFMDVFTW SLPFVGEKVTEMLVNVLNICSDDEL GSEEDGFDGATAAARKEVIRNKIRA IGKMARVFSVLREESESVLTLKGLT PTGMLPSGVLSGGKQTLQSAIKGFS PQHKITSFEEAKGLDRINERMPPRR DAMPSDANLNSINKALTSETNGTDS NGSNSSNIQ
• Sequence Similarities: Belongs to the PPP phosphatase family. PP-2B subfamily.

Gene Information

• Gene Name: PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme [ Homo sapiens ]
• Official Symbol: PPP3CA
• Synonyms: PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; CALN, CALNA, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); serine/thr
• Gene ID: 5530
• mRNA Refseq: NM_000944
• Protein Refseq: NP_000935
• MIM: 114105
• Uniprot ID: Q08209
• Chromosome Location: 4q24
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem
• Function: calcium ion binding; calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; hydrolase activity; protein binding