||Recombinant Human DPP9 (full length) was expressed in aBaculovirus infected Sf9cell expression system with N-terminal GST tag. MW=122.6 kDa.
||Dipeptidyl peptidase 9 is an enzyme that in humans is encoded by the DPP9 gene.This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.
||25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
||Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
||>6 months at -80°C.