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Recombinant Human PRSS8

Cat.No.: PRSS8-30709TH
Product Overview: Recombinant full length Human PRSS8 with N-terminal proprietary tag. Predicted MW 63.47kDa.
Description: This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
Protein length: 343 amino acids
Molecular Weight: 63.470kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVA PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWV LSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANA SFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRET CNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW IQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGL LRPILFLPLGLALGLLSPWLSEH
Sequence Similarities: Belongs to the peptidase S1 family.Contains 1 peptidase S1 domain.
Gene Name: PRSS8 protease, serine, 8 [ Homo sapiens ]
Official Symbol: PRSS8
Synonyms: PRSS8; protease, serine, 8; prostasin;
Gene ID: 5652
mRNA Refseq: NM_002773
Protein Refseq: NP_002764
MIM: 600823
Uniprot ID: Q16651
Chromosome Location: 16p11.2
Function: peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity; sodium channel regulator activity;

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