Recombinant Human PSMA2, His-tagged
Cat.No. : | PSMA2-31102TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 3-234 of Human Proteasome 20S alpha 2 with N terminal His tag; 232 amino acids, 28kDa. |
- Specification
- Gene Information
- Related Products
Description : | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 57 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | ERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAAN GVVLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMG PDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQE YTQSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAW KATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLK ESFEGQMTEDNIEVGICNEAGFRRLTPTEVKDYLAAIA |
Sequence Similarities : | Belongs to the peptidase T1A family. |
Gene Name : | PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 [ Homo sapiens ] |
Official Symbol : | PSMA2 |
Synonyms : | PSMA2; proteasome (prosome, macropain) subunit, alpha type, 2; proteasome subunit alpha type-2; HC3; MU; PMSA2; |
Gene ID : | 5683 |
mRNA Refseq : | NM_002787 |
Protein Refseq : | NP_002778 |
MIM : | 176842 |
Uniprot ID : | P25787 |
Chromosome Location : | 7p13 |
Pathway : | APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; |
Function : | peptidase activity; protein binding; threonine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
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PSMA2-4422R | Recombinant Rat PSMA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMA2-01H | Recombinant Human PSMA2 Protein isoform 1, C-His-tagged | +Inquiry |
PSMA2-4763R | Recombinant Rat PSMA2 Protein | +Inquiry |
PSMA2-2010H | Recombinant Human PSMA2, GST-tagged | +Inquiry |
◆ Lysates | ||
PSMA2-2779HCL | Recombinant Human PSMA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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