"PTS" Related Products

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Recombinant Human PTS, His-tagged

Cat.No.: PTS-31260TH
Product Overview: Recombinant full length Human PTS with N terminal His tag; 165 amino acids, MWt 18.5 kDa.
Description: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
Conjugation: HIS
Source: E. coli
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMV MNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE
Sequence Similarities: Belongs to the PTPS family.
Gene Name: PTS 6-pyruvoyltetrahydropterin synthase [ Homo sapiens ]
Official Symbol: PTS
Synonyms: PTS; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl tetrahydrobiopterin synthase; PTPS;
Gene ID: 5805
mRNA Refseq: NM_000317
Protein Refseq: NP_000308
MIM: 612719
Uniprot ID: Q03393
Chromosome Location: 11q22.3
Pathway: Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem;
Function: 6-pyruvoyltetrahydropterin synthase activity; identical protein binding; lyase activity; metal ion binding; protein homodimerization activity;

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