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Recombinant Human RARG, His-tagged

Cat.No.: RARG-31060TH
Product Overview: Recombinant full length Human Retinoic Acid Receptor gamma with His tag expressed in a baculovirus system, 51kDa.
Description: This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Conjugation: HIS
Biological activity: 1 unit is equal to 1 nanogram of purified protein.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: RARG retinoic acid receptor, gamma [ Homo sapiens ]
Official Symbol: RARG
Synonyms: RARG; retinoic acid receptor, gamma; retinoic acid receptor gamma; NR1B3; RARC;
Gene ID: 5916
mRNA Refseq: NM_000966
Protein Refseq: NP_000957
MIM: 180190
Uniprot ID: P13631
Chromosome Location: 12q13
Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem;
Function: DNA binding; metal ion binding; protein binding; receptor activity; retinoic acid receptor activity;

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